Antiplasmodial and antileishmanial activities of compounds from Piper tuberculatum Jacq fruits
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چکیده
منابع مشابه
Antinociceptive effect of crude extract, fractions and three alkaloids obtained from fruits of Piper tuberculatum.
This study investigated the possible antinociceptive effect of the crude extract, fractions and pure compounds (three alkaloids) obtained from fruits of Piper tuberculatum JACQ. (Piperaceae) in acetic acid-induced visceral pain in mice. Oral administration of crude extract and fractions (CH(2)Cl(2), EtOAc, methanol and hexane) (3-300 mg kg(-1)) caused a dose-related and significant inhibition o...
متن کاملAntiparasitic Activity and Essential Oil Chemical Analysis of the Piper Tuberculatum Jacq Fruit
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there wasa need for the search for new therapeutic alternatives that reduce the harm caused by medicineavailable for treatment. Thus, this study was performed to investigate the antiparasitic activityof the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmaniabraziliensis (MHOM/CO/8...
متن کاملAntiparasitic Activity and Essential Oil Chemical Analysis of the Piper Tuberculatum Jacq Fruit
With the increase of neglected diseases such as leishmaniasis and Chagas disease, there wasa need for the search for new therapeutic alternatives that reduce the harm caused by medicineavailable for treatment. Thus, this study was performed to investigate the antiparasitic activityof the essential oil from the fruits of Piper tuberculatum Jacq, against lines of Leishmaniabraziliensis (MHOM/CO/8...
متن کاملProteomic profile of Piper tuberculatum (Piperaceae).
Piper tuberculatum (Piperaceae) is a species that accumulates especially amides as secondary metabolites and several biological activities was previously reported. In this article, we report a proteomic study of P. tuberculatum. Bidimensional electrophoresis (2D SDS-PAGE) and mass spectrometry (ESI-Q-TOF) were used in this study. Over a hundred spots and various peptides were identified in this...
متن کاملStudy of the in vitro antiplasmodial, antileishmanial and antitrypanosomal activities of medicinal plants from Saudi Arabia.
The present study investigated the in vitro antiprotozoal activity of sixteen selected medicinal plants. Plant materials were extracted with methanol and screened in vitro against erythrocytic schizonts of Plasmodium falciparum, intracellular amastigotes of Leishmania infantum and Trypanosoma cruzi and free trypomastigotes of T. brucei. Cytotoxic activity was determined against MRC-5 cells to a...
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ژورنال
عنوان ژورنال: Revista da Sociedade Brasileira de Medicina Tropical
سال: 2018
ISSN: 1678-9849,0037-8682
DOI: 10.1590/0037-8682-0309-2017